Marin Cilic and Stan Wawrinka claimed straightforward first-round wins at the Fever-Tree Championships.
John Isner beat Radu Albot in the Lyon Open to set up a clash against Cameron Norrie.
David Goffin was made to work for his win while Tomas Berdych was beaten by Denis Shapovalov.
Stan Wawrinka's comeback was a short one, but three Americans advanced at the Italian Open.
Milos Raonic claimed the scalp of Grigor Dimitrov at the Madrid Open.
John Isner made it eight wins in a row as he reached the quarter-finals in Houston.
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With the Miami Open upon us, our resident expert offers some top tips on where to put your money.
It was a day of upsets at the Delray Beach Open as Jack Sock, John Isner and Milos Raonic crashed out.
Jack Sock kicked off the defence of his Delray Beach Open title with a win while Hyeon Chung also advanced.