Kevin Anderson, David Ferrer advance in Mexico, but John Isner out

Fifth seed Kevin Anderson and former champion David Ferrer advanced at the Abierto Mexicano Telcel, but John Isner tumbled out.

South African Anderson had no problems seeing off Radu Albot, claiming a 6-4, 6-3 victory over the Moldovan to set up a second-round clash against either Adrian Mannarino of France or Ricardas Berankis of Lithuania.

Four-time champion Ferrer was way too good for Andrey Rublev, who beat him at the Australian Open in January, as he secured a 6-4, 6-3 win over the 20-year-old.

The Spaniard raced into a 5-1 lead in the first set before Rublev staged a comeback, but it was short-lived as the veteran wrapped up the set in 36 minutes.

Ferrer claimed an early break of serve in the second set as he went 3-0 up, and he didn’t look back after that.

He will face either fifth seed Juan Martin del Potro or Mischa Zverev of Germany in the second round.

American Jared Donaldson also advanced is he was leading 6-2, 3-2 when Georgian Nikoloz Basilashvili retired.

In an all-American battle, Ryan Harrison upset eighth seed John Isner 6-3, 7-6 (7-5) and his reward is a second-round encounter against either Rio Open champion Diego Schwartzman or Fernando Verdasco.